Jurgen Klopp up to face a challenging time with not less than a dozen of his first-team squad members got called up for international duty ahead of the Merseyside derby.

Brazilian duo Philippe Coutinho and Robert Firmino would commence a most arduous trip to take part in two world cup qualifying match in South America.

The Brazil national team would clash against Uruguay in Montevideo on Thursday and Afterwards takes on Paraguay in Sao Paulo on Wednesday. Coutinho and Firmino would then make a return to Merseyside – returning to Melwood just two days ahead of the clash with Everton.

The Reds England contingent has been afflicted with injuries with Jordan Henderson sidelined with a foot injury and Daniel Sturridge nursing ankle injury. Adam Lallana and Nathaniel Clyne on the other hand would be participating in England,s friendly match with Germany on Wednesday and the World Cup qualifying match at Wembley Stadium on Sunday.

Joe Gomez is part of the England Under-21 squad that takes on Germany and Denmark, while Trent Alexander-Arnold would be playing with England Under-19s for their elite round qualifiers against Spain, Norway and Belarus.

Simon Mignolet and Divock Origi have joined the Belgian team to take on Greece on Saturday in their World Cup qualifying home match and afterwards would go on to a friendly against Russia in Sochi.

Ragnar Klavan would captain the Estonia national team in their Qualifier in Cyprus on Saturday and the left-footed centre-back would possibly appear in a friendly with Croatia next Tuesday.

Klopp would worry less about Sadio Mane’s during this international break. Senegal face Nigeria at Barnet FC on Thursday before facing off with Ivory Coast in Paris on Monday.

Reds midfielders Gini Wijnaldum and Emre Can, after an outstanding display in the 1-1 draw with Manchester City on Sunday, are also away.

Wijnaldum joined the Netherlands team in preparation for the World Cup qualifier against Bulgaria in Sofia on March 25 and a friendly against Italy three days afterwards.

Can got called up to Germany national team for their Friendly against England at Westfalenstadion on Wednesday night and then goes off to Azerbaijan for a World Cup qualifier in Baku on March 26.

James Milner and Joel Matip are the only members of Liverpool first team remaining at Anfield as they have both retired from international duty.

The only members of Liverpool’s starting XI from Sunday’s showdown at the Etihad Stadium who haven’t gone away are James Milner and Joel Matip, who have both retired from international duty.